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Clinical Child Psychology and Psychiatry, Vol. 9, No. 4, 597-603 (2004)
DOI: 10.1177/1359104504046163
© 2004 SAGE Publications

Separation Anxiety Triggered by Atypical Neuroleptic Medication in an Adolescent with Tourette’s Syndrome

Katja Becker

Central Institute of Mental Health, Mannheim, Germanykbecker{at}zi-mannheim.de

Martin Holtmann

Mahha El-Faddagh

Martin H. Schmidt

Central Institute of Mental Health, Mannheim, Germany

This article describes the case of a 13-year-old male Tourette’s syndrome patient who developed separation anxiety disorder during combined treatment with risperidone and tiapride. In the 1980s, neuroleptic separation anxiety syndromes in patients with Tourette’s syndrome were described, and an association between the neuroleptic medication and the induced separation anxiety disorder in our patient seems probable. We conclude that future investigations of atypical anti-psychotics and their possible tendency to elicit separation anxiety are essential. Physicians should pay attention to the occurrence or exacerbation of separation anxiety in patients with Tourette’s syndrome who are receiving either typical or atypical neuroleptics.

Key Words: neuroleptics • separation anxiety • side effects • tiapride • Tourette’s syndrome


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